Ma`rifat Farhangi Ejtemaei

One of the fundamental issues in the field of Islamic human sciences is the question of the *possibility*, *nature*, and *method* of realizing religious knowledge. Ayatollah Mohammad-Taqi Misbah Yazdi is among the contemporary scholars who, through a philosophical-theological approach, has presented a coherent theory on this matter. He argues that Western human sciences are founded upon *materialistic*, *secular*, and *humanistic* presuppositions and therefore cannot, without a fundamental reconsideration of their foundations, meet the needs of an Islamic society. According to his view, the *Islamization of the human sciences* does not merely mean adding religious propositions to existing scientific frameworks but rather requires a complete reconstruction of the conceptual system, epistemological foundations, and scientific ends based on a *monotheistic worldview*. In this article, using an *analytical-critical* method, the philosophical foundations of Ayatollah Misbah Yazdi’s theory of religious knowledge—including its ontological, epistemological, and anthropological principles—are examined and analyzed. The study also explores the role of *reason*, *experience*, and *revelation* in the process of producing religious knowledge and its relationship with the methodology of modern human sciences. The findings indicate that his theory possesses the capacity to establish an alternative framework for Islamic human sciences—one that can both critique secular foundations and contribute to the formation of a new epistemic system. This analysis may open new horizons in the transformation of human sciences and the realization of a *new Islamic civilization*.